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标题：CHARACTERIZATION OF THE INTERACTION OF ALBUMIN WITH ISOLATED RAT LIVER CELLS TO REVEAL THE MECHANISM OF ALBUMIN-MEDIATED HEPATIC TRANSPORT
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作者：TAKASHI MIZUMA ; TOSHIHARU HORIE ; MASAHIRO HAYASHI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1986
卷号：9
期号：3
页码：244-248
DOI：10.1248/bpb1978.9.244
出版社：The Pharmaceutical Society of Japan
摘要：The binding of bovine serum albumin (BSA), containing ¹²⁵I-BSA, to isolated rat hepatocytes was studied over a 300-fold concentration range of BSA to characterize the interaction between albumin and the liver cells in albumin-mediated hepatic transport. The binding of BSA with a high affinity to the cell surface of hepatocytes was not found in the binding behavior. The bound fraction of BSA with hepatocytes was about 1% over those concentration range of BSA.
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