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标题：QUANTITATIVE DETERMINATION OF THE SUPEROXIDE RADICALS IN THE XANTHINE OXIDASE REACTION BY MEASUREMENT OF THE ELECTRON SPIN RESONANCE SIGNAL OF THE SUPEROXIDE RADICAL SPIN ADDUCT OF 5, 5-DIMETHYL-1-PYRROLINE-1-OXIDE
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作者：IKUKO UENO ; MASAHIRO KOHNO ; KUNITOSHI YOSHIHIRA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1984
卷号：7
期号：8
页码：563-569
DOI：10.1248/bpb1978.7.563
出版社：The Pharmaceutical Society of Japan
摘要：Reactivities of biologically active compounds with superoxide radicals were examined by measurement of electron spin resonance (ESR) spectra of 5-hydroperoxy-2, 2-dimethy 1-1-pyrrolidinyloxyl formed from 5, 5-dimethyl-1-pyrroline-1-oxide and the superoxide radicals generated by xanthine-xanthine oxidase system. Quantitative determination of the superoxide rachcals was performed by comparing the intensity of the spin adducts with chat of 4-hydroxy-2, 2, 6, 6-tetramethyl-pipperi-dinooxyl whose spin concentration was determined. Methyl viologen enhanced the formation of this spin adducts, while, rutin and luteoskyrin prevented it.
关键词：luteoskyrin