文章基本信息

标题：INTESTINAL ABSORPTION OF URSODEOXYCHOLIC, GLYCOURSODEOXYCHOLIC AND TAUROURSODEOXYCHOLIC ACIDS IN RATS
本地全文：下载
作者：MASAMICHI OTA ; YASUMASA MINAMI ; TAKAHIKO HOSHITA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1985
卷号：8
期号：2
页码：114-118
DOI：10.1248/bpb1978.8.114
出版社：The Pharmaceutical Society of Japan
摘要：We examined the intestinal absorption of ursodeoxycholic acid (UDC), glycoursodeoxycholic acid (GUDC) and tauroursodeoxycholic acid (TUDC) using an everted gut sac technique. UDC was absorbed throughout rat small intestine almost to the same extent. Absorption of both GUDC and TUDC, however, varied between jejunum and ileum. Absorption of these conjugated bile acids in the jejunal segments was less than that of UDC. While, absorption of GUDC and TUDC in the terminal ileum was more efficient than UDC. Although 2, 4-dinitrophenol had no effect on the jejunal uptake, ileal uptake of these three bile acids was inhibited by 2, 4-dinitrophenol.
关键词：cholelithiasis