文章基本信息

标题：THE EFFECT OF ALBUMIN ON THE UPTAKE OF BROMOSULFOPHTHALEIN BY ISOLATED RAT HEPATOCYTES
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作者：TAKASHI MIZUMA ; TOSHIHARU HORIE ; SHOJI AWAZU 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1985
卷号：8
期号：2
页码：90-94
DOI：10.1248/bpb1978.8.90
出版社：The Pharmaceutical Society of Japan
摘要：The initial rate of uptake of bromosulfophthalein (BSP) by isolated rat hepatocytes analyzed as a function of the unbound concentration of BSP was greater in the presence of albumin than in its absence, though the presence of albumin in the medium apparently decreased the uptake of BSP by hepatocytes analyzed as a function of the total concentration of BSP. This suggests that the uptake of BSP by isolated rat hepatocytes in the presence of albumin is not only dependent on the unbound concentration of BSP, but also is driven by the bound fraction of BSP.
关键词：bromosulfophthalein