文章基本信息

标题：STRUCTURE-ACTIVITY RELATIONSHIP OF THIRTY-NINE CYTOCHALASANS OBSERVED IN THE EFFECTS ON CELLULAR STRUCTURES AND CELLULAR EVENTS AND ON ACTIN POLYMERIZATION IN VITRO
本地全文：下载
作者：SETSUKO SEKITA ; KUNITOSHI YOSHIHIRA ; SHINASAKU NATORI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1985
卷号：8
期号：11
页码：906-916
DOI：10.1248/bpb1978.8.906
出版社：The Pharmaceutical Society of Japan
摘要：The effects of twenty-three natural cytochalasans and sixteen synthetic derivatives on actin-distribution and alteration in morphology of C3H-2K cells, inhibition of lymphocyte capping, and inhibition of actin filament elongation were compared. The effects on cellular level and the in vitro effects showed positive correlation and the structure-activity relationship observed is discussed.
关键词：structure-activity relationship