文章基本信息

标题：Production and Some Properties of Monoclonal Antibodies against Serotype Strains of Pseudomonas aeruginosa
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作者：Kenji YOSHIDA ; Fumio KIMURA ; Kyoko UCHIDA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1989
卷号：12
期号：7
页码：398-404
DOI：10.1248/bpb1978.12.398
出版社：The Pharmaceutical Society of Japan
摘要：A set of 16 serotype specific monoclonal antibodies (MoAbs) against Pseudomonas aeruginosa classified by Homma were obtained by the mouse hybridoma technique. This set of MoAbs was useful for classification of their serotypes especially O-antigen groups G and M. MoAb obtained from serotype 15 of Homma's classification reacted with serotype 17 of the same classification. We also obtained two MoAbs which reacted with 7 Homma's serotypes of 6 different O-antigen groups and one MoAb which recognized all 4 Homma's serotypes of O-antigen group B. These MoAbs were also useful in mice for the preventive effect against the infections of P. aeruginosa.
关键词：mouse