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标题：TRANSPORTATION OF COPPER IN RABBIT BLOOD
本地全文：下载
作者：Kyoko MURAKAMI ; Shinzo TANABE ; Koreharu OGATA 等
期刊名称：Industrial Health
印刷版ISSN：0019-8366
电子版ISSN：1880-8026
出版年度：1981
卷号：19
期号：3
页码：185-189
DOI：10.2486/indhealth.19.185
出版社：National Institute of Occupational Safety and Health
摘要：Copper sulfate was given to male rabbits intraperitoneally and the copper concentrations in the plasma, red cells and EtOH-CHCl₃ treated fraction of the cells were determined. The concentration of copper in the plasma increased markedly and in the red cells increased slightly after administration of 1 mg copper/kg of body weight, while the copper level in the EtOH-CHCl₃ treated fraction remained constant. In this experiment, the ceruloplasmin activity in the plasma increased, while the superoxide dismutase activity in the red cells remained unchanged. The form of the copper present in the plasma was also examined by gel filtra-tion on a Sephadex G-150 column. Most of the copper absorbed in the plasma appeared at first in the albumin fractions and was then incorporated into cerulo-plasmin fractions.
关键词：Copper;Blood;Albumin;Ceruloplasmin;Superoxide dismutase;Trans-portation;Rabbit