文章基本信息

标题：ORIGINAL ARTICLES
本地全文：下载
作者：Tohru HASEGAWA ; Yukio HIRAI ; Naomi KOGA 等
期刊名称：Industrial Health
印刷版ISSN：0019-8366
电子版ISSN：1880-8026
出版年度：1983
卷号：21
期号：4
页码：231-234
DOI：10.2486/indhealth.21.231
出版社：National Institute of Occupational Safety and Health
摘要：The hepatic mitochondrial and microsomal recovery of rats intoxicated with CCl₄ was investigated with specific reference to the oxygen utilization of liver slices. In control rats, the major oxygen utilization of the liver slices was at-tributed to mitochondrial particles. Since the mitochondrial oxygen utilization was inhibited by cyanide, the microsomal oxygen utilization was induced by NADPH and phenobarbital (a substrate for microsomal mixed function oxidase). Changes in oxygen utilization were observed in the recovery course of rats intoxicated with CCl₄, and the recovery of mitochondria was found to be faster than that of micro-somes. A sex difference was present in the recovery mechanism of the microsomes.
关键词：Key words : Recovery-Mitchondria-Microsomes-Oxgen uptake-CCl4