期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1978
卷号:24
期号:3
页码:297-309
DOI:10.3177/jnsv.24.297
出版社:Center for Academic Publications Japan
摘要:Hematological changes due to protein deprivation were studied in 34 young Japanese men who were given a standard diet with an N intake of 200 mg/kg for one week and then low-protein diets with maintenance (45±2 kcal/kg) or excess (57±2 kcal/kg) energy and N intakes of about 44 to 99mg/kg of whole egg or about 50 to 121mg/kg of polished rice for three weeks. In the period of the low-protein diet the concentrations of most individual free plasma essential amino acids (EAA) decreased significantly in general, and thus the total FAA concentration decreased significantly. Lowering of the valine concentration and elevation of the alanine concentration were the highest changes. The total non essential amino acid (NEAA) concentration increased significantly in men fed a low-rice-protein diet, but not in those fed a low-egg-protein diet. Consequently, in the former group the ratio of essential to nonessential amino acids fell significantly from 0.96 in the control period to 0.61-0.74 in the period of consuming the low-protein diet. The effect of protein deprivation on the plasma EAA concentration was also larger with egg protein than with rice protein, and the total FAA concentration of men fed egg protein changed significantly and in parallel with the N intake over the range of 44 to 99mg/kg. The decreases in serine and threonine and increase in alanine tended to be more when energy intake was over the maintenance level. The concentration of plasma proteins and especially albumin decreased significantly during the period of consuming the low-protein diet. The interrelation of plasma-free amino acids, the amino acid pool in tissues and dietary N and energy intakes is briefly discussed.