文章基本信息

标题：Isolation and Characterization of a Coupled Compound of Thiamin with Catechol
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作者：Fumiko HAYAKAWA ; Kiyoshi UEDA ; Kiku MURATA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1984
卷号：30
期号：4
页码：327-334
DOI：10.3177/jnsv.30.327
出版社：Center for Academic Publications Japan
摘要：Equimolecular amounts of thiamin and catechol incubated under suitable conditions produced an unknown reaction product isolated as a light yellow powder from the reaction mixture by reverse-phase ODS column chromatography. Elemental analysis of the purified powder showed the molecular formula to be C₁₈H₂₂N₄O₄S-HCl-H₂O in agreement with a molecular ion peak found at m / e 390 in the mass spectrum. These results together with the data of IR and NMR spectrometry possibly show that this material consists of an isomeric mixture of S -3, 4 and S-2, 3-dihydroxyphenylthiamin (I and II) which probably arise as a result of oxidative addition of the thiol group of thiamin to catechol.
关键词：thiamin;catechol;thioether