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标题：The Effect of Natural Carotenoid (Palm Fruit Carotene) Intake on Skin Lipid Peroxidation in Hairless Mice
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作者：Keita SOMEYA ; Yuka TOTSUKA ; Michiaki MURAKOSHI 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1994
卷号：40
期号：4
页码：303-314
DOI：10.3177/jnsv.40.303
出版社：Center for Academic Publications Japan
摘要：To study the effect of palm fruit carotene intake on skin lipid peroxidation, hairless mice were given ad libitum palm fruit caro-tene, β-carotene, or vehicle emulsions for 15 weeks in which the carotene (0.005%, w/w) was suspended in drinking water, and then their dorsal skin was exposed to ultraviolet ray (UV). The carotene content of the skin was increased by the oral intake of palm fruit carotene or β-carotene. In carotene-drinking mice, before the UV irradiation, the amount of thiobarbituric acid-reacting substances (TBARS) in the skin was lower than that of control (carotene untreated) mice. The skin TBARS immediately after the UV irradiation was lower in carotene-treated mice than in control mice. At 24h after irradiation, the skin TBARS of mice that orally received palm fruit carotene was lower than that of β-carotene mice. Immediately after the UV irradiation, the skin carotene content transiently decreased but gradual recovery was observed at 48 h. In palm fruit carotene-treated mice, the rate of carotene recovery after UV irradiation was higher than in β-carotene-treated mice. Retinol found in the skin had also decreased after UV irradiation, and recovered gradually in both carotene-drinking groups within 48 h. These results suggested that the carotene intake, especially palm fruit carotene, prevented skin lipid peroxidation in hairless mice.
关键词：palm fruit carotene;β-carotene;lipid peroxidation;thiobar-bituric acid-reacting substances (TBARS);ultraviolet ray;anti-oxidant;skin lipid;hairless mouse