文章基本信息

标题：Serum Lipid Levels Correlate with Solid Tumor Weight in Hepatoma-Bearing Rats Fed Dietary Fish Oil
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作者：Masashi KAWASAKI ; Kazumi YAGASAKI ; Yutaka MIURA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2004
卷号：50
期号：3
页码：222-226
DOI：10.3177/jnsv.50.222
出版社：Center for Academic Publications Japan
摘要：The effects of dietary fish oil (FO) on serum lipid levels and tumor proliferation were studied in Donryu rats subcutaneously implanted with the ascites hepatoma cell line AH109A. Solid tumor weight was significantly less and serum total cholesterol (T-Ch) level significantly lower in the groups fed the FO diet both before and after AH109A implantation than in the groups fed the corn oil diet. There were no significant effects in the serum lipid levels and tumor proliferation in the groups fed the FO diet only before or after the hepatoma implantation. The serum triacylglyceride, phospholipid, nonesterified fatty acid, T-Ch, and very-low-density lipoprotein+low-density lipoprotein-Ch levels showed significant positive correlations with the solid tumor weight. These results suggest that dietary FO ingestion after hepatoma implantation suppresses tumor proliferation and reduces serum lipid levels along with suppressing tumor proliferation.
关键词：dietary fish oil;hepatoma;hyperlipidemia;serum lipid level;solid tumor proliferation