文章基本信息

标题：HEMODILUTION AND IRON METABOLISM IN RATS DURING PREGNANCY
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作者：Keizo SHIRAKI ; Fumiko HISAOKA ; Sueko SAGAWA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1973
卷号：19
期号：5
页码：455-463
DOI：10.3177/jnsv.19.455
出版社：Center for Academic Publications Japan
摘要：Studies were made on the cellular components of the blood, the serumiron concentration, and the circulating blood and plasma volumes of rats in pregnancy and on the iron transport from the maternal blood to the conception products (uterus and its contents) using radioactiveiron. Anemia of pregnancy developed and was most pronounced during late pregnancy when the conception products developed rapidly. The reticulocyte count did not increase significantly, so that there is no evidence for stimulation of hematopoiesis during pregnancy of rats. The circulating blood and plasma volumes increased significantly during late pregnancy, but the total hemoglobin and red cell volume did not increase. The anemia in pregnancy of rats was due to hemodilution, but this hemodilution occurred in different grades in comparison with human pregnancy. The iron concentration of the serum decreased most during late pregnancy when development of the conception products was greatest and placental transport of iron to the fetus was largest.