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标题：Effect of Dietary Cabbage Fermentation Extract and Young Barley Leaf Powder on Immune Function of Sprague-Dawley Rats
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作者：Yoshiyuki MIYAZAKI ; Yoko TOKUNAGA ; Kinya TAKAGAKI 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2001
卷号：47
期号：3
页码：253-257
DOI：10.3177/jnsv.47.253
出版社：Center for Academic Publications Japan
摘要：We investigated dietary effects of cabbage fermentation extract (CFE) and young barley leaf powder (YBLP) on rat immune functions. Male Sprague-Dawley rats of 4 wk age were fed for 3 wk diets containing these samples at 0.1 or 1% level. After the feed-ing period, serum IgG level was significantly higher in the rats fed 1% CFE. IgG productivity of spleen lymphocytes was enhanced dose-dependently in both groups of CFE and YBLP. Furthermore, IgG productivity of mesenteric lymph node (MLN) lymphocytes was approxi-mately 2 times higher in the rats fed 1% CFE diet than in the control ones. IgA productivity of MLN lymphocytes tended to increase in both of CFE and YBLP groups. From these results, it was suggested that dietary CFE and YBLP reinforced Ig productivity in both systemic and intestinal immune systems. Moreover, CFE feeding tended to enhance the production of TNF-α by spleen lymphocytes. In spleen phospholipids, the level of arachidonic acid, a sub-strate for inflammatory lipid mediators, was not affected by CFE or YBLP feeding.
关键词：cabbage fermentation extract;young barley leaf powder;serum immunoglob-ulin level;immunoglobulin production;rat lymphocytes