期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1974
卷号:20
期号:3
页码:189-196
DOI:10.3177/jnsv.20.189
出版社:Center for Academic Publications Japan
摘要:Thiamine transport by the red blood cells of rats was investigated at a physiological concentration of thiamine. The transport rate became large in accordance with the decrease of the initial thiamine concentration in the medium. Pyrithiamine and chloroethylthiamine inhibited this transport but oxythiamine did not. The examination of counter flow showed that thiamine efflux from the red blood cells after preloading was accelerated by thiamine added in the medium. However, the metabolic energy was not required for the thiamine transport by the red blood cells. This evidence indicates that thiamine is taken up by facilitated diffusion by the red blood cells of rats at a physiological concentration of thiamine.