文章基本信息

标题：Liver Damage among Environmental Disinfestation Workers
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作者：Francesco TOMEI ; Marco BIAGI ; Tiziana Paola BACCOLO 等
期刊名称：Journal of Occupational Health
印刷版ISSN：1341-9145
电子版ISSN：1348-9585
出版年度：1998
卷号：40
期号：3
页码：193-197
DOI：10.1539/joh.40.193
出版社：Japan Society for Occupational Health
摘要：Liver Damage among Environmental Disinfestation Workers: Francesco TOMEI, et al. Occupational Medicine Dept., “La Sapienza” University, Rome -It has been reported that exposure to high doses of insecticides can damage the liver. It is now becoming apparent that even exposure to low doses may affect the liver and blood. Studies on the effects on the health of disinfestation workers are scant. This study investigated 37 males doing environmental disinfestation work. They all employed the same types and amounts of pesticides. They were compared with 60 controls not exposed to hepatotoxic substances. In the presence of a physician, all subjects completed a clinical-history questionnaire. They all underwent a general clinical examination and specific blood chemistry tests were done. In the exposed group we found liver test values to be higher than controls (p<0.001), including AST (p<0.025), alkaline phosphatase (p<0.001 ), and total bilirubin (p<0.001 ). We found no abnormal hematological changes. The findings indicate that the use of pesticides in environmental disinfestation alters liver function and that this screening protocol is valid for identifying subjects at risk for he atotoxicity.
关键词：Disinfestation workers;Insecticides;Low dose;Hepatotoxicity;Blood effects