文章基本信息

标题：Physiological Impairment in Linoleic Acid Deficiency of Rats and the Effect of n-3 Polyunsaturated Fatty Acids
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作者：Nobuko IRITANI ; Yumiko IKEDA ; Hitomi FUKUDA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1984
卷号：30
期号：2
页码：179-185
DOI：10.3177/jnsv.30.179
出版社：Center for Academic Publications Japan
摘要：Some impairments related to membrane function were found in linoleic acid-deficient rats and the effects of fish oil feeding were investigated. In linoleic acid-deficient rats, glucose transport into erythrocytes was decreased. The concentrations of plasma free fatty acids were significantly reduced in the animals. Further, epinephrine-stimulated lipase was remarkably less sensitive to epinephrine in the deficient rat than in the corn oil-fed control rat. However, these impairments were relieved by fish oil feeding. Therefore, the impairments may be ascribed to the decrease of arachidonic acid as a polyunsaturated fatty acid in membrane phospholipids, since n -3 polyunsaturated fatty acids appear to take the place of arachidonic acid. Key Words linoleic acid deficiency, fish oil, lipolysis, glucose transport