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  • 标题:Submitochondrial Localization of Rat Liver β-Alanine Oxoglutarate Aminotransferase
  • 本地全文:下载
  • 作者:Nanaya TAMAKI ; Shigeko FUJIMOTO ; Chizuru MIZOTA
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1987
  • 卷号:33
  • 期号:6
  • 页码:439-449
  • DOI:10.3177/jnsv.33.439
  • 出版社:Center for Academic Publications Japan
  • 摘要:β-Alanine-oxoglutarate aminotransferase from rat liver was mainly distributed in the mitochondrial fraction, while β-ureidopropionase, the last one of uracil-metabolizing enzymes to β-alanine, was predominantly distributed in the cytosolic fraction. When rat liver mitochondria were separated into submitochondrial fractions, β-alanineoxoglutarate aminotransferase was localized in the mitochondrial matrix. β-Alanine was transported into mitochondria with time and the influx of β-alanine into the matrix was 0.47 nmol/mg of mitochondrial protein at 2 min after incubation.
  • 关键词:mitochondria;mitochondrial matrix;β-alanine;;β-alanineoxoglutarate aminotransferase;β-ureidopropionase
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