文章基本信息

标题：Umbilical Ascorbic Acid Levels in Fetal Distress
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作者：Michaela DVIR ; David KOHELET ; Eliana ARBEL 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1992
卷号：38
期号：5
页码：511-515
DOI：10.3177/jnsv.38.511
出版社：Center for Academic Publications Japan
摘要：Umbilical arterial and venous blood samples were obtained at birth immediately after clamping the cord in 38 infants. Simultaneously, maternal arterial samples were collected. Arterial blood samples were analyzed for acid-base blood gas content and venous blood samples were analyzed for plasma ascorbic acid levels. The umbilical plasma ascorbic acid level was significantly higher when compared with maternal plasma levels (172.9±39.2 vs . 57.8±21.0, tmol/liter, p <0.0001). Correlations between maternal ascorbic acid levels and umbilical cord levels proved to be insignificant. Umbilical ascorbic acid levels in the 2 groups of infants characterized by the presence or absence of fetal distress showed signifi-cantly higher levels in the fetal distressed group (17 infants) when compared to the non-distressed group (21 infants)-191.9±36.0 vs . 157.4 ±34.6μmol/liter, p <0.005. The use of an umbilical cord ascorbic acid cut-off point of 95.8μmol/liter gave a sensitivity of 76% and a specificity of 67% as predictors for the presence or absence of fetal distress ( p <0.025). The results of the present study demonstrate a substantial increase in ascorbic acid levels in infants exposed to intrapartum fetal distress, without any clinical sign of such insult at or after birth.
关键词：asphyxia;fetal distress;neonate