文章基本信息

标题：Plasma β-Carotene, Retinol, and α-Tocopherol Levels in Relation to Glycemic Control of Children with Insulin-Dependent Diabetes Mellitus
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作者：Masatoshi HOZUMI ; Takuji MURATA ; Takao MORINOBU 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1998
卷号：44
期号：1
页码：1-9
DOI：10.3177/jnsv.44.1
出版社：Center for Academic Publications Japan
摘要：Plasma β-carotene, α-tocopherol and retinol were measured in 15 female and 5 male children with insulin-dependent diabetes mellitus (IDDM), and the correlations with plasma hemoglobin Ale (HbA 1 c) and fructosamine were analyzed. Twelve female and 8 male children served as age-matched controls. The plasma β-carotene and α-tocopherol levels of the IDDM children were significantly higher than those of the control children, but there were no differences in plasma retinol or total lipid levels. The plasma β-carotene level, β-carotene/retinol ratio and β-carotene/total lipids ratio each showed significant correlations with serum HbAlc and fructosamine in all subjects studied. Similarly, the plasma α-tocopherol level and α-tocopherol/total lipids ratio were correlated with these indexes of glycemic control. These findings suggest certain mechanisms may exist to prevent lipid peroxidation and vascular complications in IDDM patients.
关键词：α-tocopherol;β-carotene;retinol;diabetes mellitus;HbAlc