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标题：Microencapsulated Ferrous Sulfate to Fortify Cow Milk: Absorption and Distribution in Mice
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作者：Jose R. BOCCIO ; Marcela B. ZUBILLAGA ; Ricardo A. CARO 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1998
卷号：44
期号：3
页码：381-389
DOI：10.3177/jnsv.44.381
出版社：Center for Academic Publications Japan
摘要：To determine the absorption and biodistribution of iron from microencapsulated ferrous sulfate (SFE-171), used to fortify dairy products with iron, a comparative study in four groups of 30 mice each was carried out. In two of the groups, the absorption of iron from ferrous ascorbate in water (13.3±4.3%) and from ferrous sulfate in water (12.7±3.9%) was determined and taken as reference standards. In the third group the iron absorption from SFE-171 in milk was determined, giving a value of 12.1±4.2%, which statistically does not differ from the data obtained with either reference standard. In the fourth group, the absorption of iron from ferrous sulfate in milk showed a value of 7.7±3.4%, which statistically differs with a p <0.01 from the data corresponding to the other three groups. The biodistribution studies showed that the iron from SFE-171 follows the same metabolic pathway as the iron from the reference standards thus, giving a higher radioac-tivity percentage and radioactivity concentration in organs or systems, principally blood, that are closely related to iron metabolism. Our studies allow us to conclude that the iron from SFE-171 in milk follows the same behavior as the nonhemic iron, with a higher absorption than that of ferrous sulfate in milk.
关键词：milk;fortification;iron;metabolism;absorption