文章基本信息

标题：Relationship Between Dehydroepiandrosterone Sulfate and Serum Lipid Levels in Japanese Men
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作者：Kazushi Okamoto
期刊名称：Journal of Epidemiology
印刷版ISSN：0917-5040
电子版ISSN：1349-9092
出版年度：1996
卷号：6
期号：2
页码：63-67
DOI：10.2188/jea.6.63
出版社：Japan Epidemiological Association
摘要：The relationships between Dehydroepiandrosterone sulfate (DHEAS) level and atherosclerosis were studied using 90 men who received a general medical examination in their company. The mean serum DHEAS level was 1510.2ng/ml, while the frequency distribution was skewed to a lower value. A marked linear decline of levels with age was observed. DHEAS levels were positively correlated with high density lipoprotein-choresterol (HDLC) (r=0.22, p<0.05), and negatively correlated with low density lipoprotein-choresterol (LDLC) (r=-0.31, p<0.001), even after adjustment for age. The mean Atherogenic Index (AI) was significant inversely correlated with rise of tertiles of the DHEAS level, both before and after adjustment for age, total cholesterol (TC), HDLC and triglyceride (TG). These results suggest that DHEAS may have an important role in the etiology and prevention of atherosclerosis. J Epidemiol , 1996; 6 : 63-67.
关键词：dehydroepiandrosterone sulfate;serum lipids;atherosclerosis;cross-sectional study