文章基本信息

标题：Serum α 1-Antichimotrypsin Levels and Cardiovasucular Risk Factors in the Japanese Elderly Population:
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作者：Kazushi Okamoto ; Takashi Ito ; Kiyoko Yagyu 等
期刊名称：Journal of Epidemiology
印刷版ISSN：0917-5040
电子版ISSN：1349-9092
出版年度：1998
卷号：8
期号：2
页码：94-98
DOI：10.2188/jea.8.94
出版社：Japan Epidemiological Association
摘要：In recent years, an elevated serum α 1-antichimotrypsin (ACT) levels is associated with increased risk of Alzheimer-type dementia. The relationship between ACT and conventional various cardiovascular risk factors were studied using 589 noninstitutionalized individuals aged 65 and older living in the community in Japan. Serum ACT levels had no significantly differences between men and women, and had no significantly association with age in both sexes. Serum ACT levels had no statistically significant associated with body mass index, blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol in both sexes. There were no significant differences in mean of serum ACT levels between in subjects with prevalent and subclinical cardiovascular disease and in those who were free of disease. A prospective study design is needed to clarify the relation between ACT and the development of Alzheimer-type dementia. J Epidemiol , 1998 ; 8 : 94-98.
关键词：α 1-antichimotrypsin;dementia;cardiovascular disease;elderly;Japan