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标题：Effects of Passive Smoking on Serum Levels of Carotenoids and α-Tocopherol
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作者：Naoyoshi Takatsuka ; Norito Kawakami ; Yoshinori Ito 等
期刊名称：Journal of Epidemiology
印刷版ISSN：0917-5040
电子版ISSN：1349-9092
出版年度：1998
卷号：8
期号：3
页码：146-151
DOI：10.2188/jea.8.146
出版社：Japan Epidemiological Association
摘要：To evaluate the effects of passive smoking identified by urine cotinine on serum carotenoids and α-tocopherol, we categorized 124 residents in a rural city of Japan into 4 groups by their urine cotinine/creatinine (Cot/Cr) ratio (u.d. (undetectable); low (0-50 ng/mg); moderate (50-120ng/mg); high (>120 ng/mg)) and compared the serum carotenoids and a-tocopherol levels among these groups. We identified passive smoking by low Cot/Cr ratio level. After controlling on related factors, men with low Cot/Cr ratio showed significantly lower serum zeaxanthin/lutein levels than men with u.d. Cot/Cr ratio. The difference was still marginally significant after excluding selfreported current smokers from the low Cot/Cr group. It is suggested that low level exposure to tobacco smoke, which has been reported to be equivalent to that for passive smokers, could be associated with decreased serum zeaxanthin/lutein levels in men.J Epidemiol, 1998 ; 8 : 146-151.
关键词：passive smoking;urine cotinine;carotenoids;α-tocopherol