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  • 标题:Antibacterial Activity of Some Garcinia Benzophenone Derivatives against Methicillin-Resistant Staphylococcus aureus
  • 本地全文:下载
  • 作者:Munekazu IINUMA ; Hideki TOSA ; Toshiyuki TANAKA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1996
  • 卷号:19
  • 期号:2
  • 页码:311-314
  • DOI:10.1248/bpb.19.311
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Benzophenone derivatives, garcinol (1) and isogarcinol (2) isolated from the pericarps of Garcinia purpurea (Guttiferae), and xanthochymol (3) and a mixture of isoxanthochymol (4) cycloxanthochymol (5) from the pericarps of G. subelliptica were evaluated for their antibacterial activity against methicillin-resistant Staphylococcus aureus. Among them, 3 showed the lowest minimum inhibitory concentration at 3.1-12.5μg/ml. This concentration is nearly equal to that of the antibiotic, vancomycin.
  • 关键词:antibacterial activity;methicillin-resistant Staphylococcus aureus;benzophenone;Garcinia subelliptica;Garcinia purpurea
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