文章基本信息

标题：Isolation and Identification of Compounds from Brazilian Propolis which Enhance Macrophage Spreading and Mobility
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作者：Tomoki TATEFUJI ; Noboru IZUMI ; Tsunetaka OHTA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1996
卷号：19
期号：7
页码：966-970
DOI：10.1248/bpb.19.966
出版社：The Pharmaceutical Society of Japan
摘要：Brazilian propolis is known to induce the activation of murine effector cells. We isolated and identified six compounds from a water-soluble extract of Brazilian propolis, all of which have enhancing effects on the spreading and mobility of murine macrophages. These compounds were identified as caffeoylquinic acid-derivatives, namely, 5-caffeoylquinic acid (1), chlorogenic acid (2), 4-caffeoylquinic acid (3), 4, 5-dicaffeoylquinic acid (4), 3, 5-dicaffeoyquinic acid (5) and 3, 4-dicaffeoylquinic acid (6).
关键词：propolis;caffeoylquinic acid;macrophage;spreading;mobility;Brazil