文章基本信息

标题：Anti-Helicobacter pylori Activity of Hearbal Medicines
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作者：Eun-Ah BAE ; Myung Joo HAN ; Nam-Jae KIM 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1998
卷号：21
期号：9
页码：990-992
DOI：10.1248/bpb.21.990
出版社：The Pharmaceutical Society of Japan
摘要：The extracts of Coptidis japonica (rhizoma), Eugenia caryophyllata (flower), Rheum palmatum (rhizoma), Magnolia officinalis (cortex) and Rhus javanica (galla rhois) potently inhibited the grow of Helicobacter pylori (HP). However, these herbal extracts showed no inhibitory effect on HP urease except Galla rhois. Among the components separated from active herbal extracts by silica gel column chromatography, the inhibitory effects of decursinal angelate and decursion on the growth of HP were the most potent, followed by magnolol, berberine, cinnamic acid, decursinol and gallic acid. Minimum inhibitory concentrations (MICs) of decursin and decursinol anglate were 6-20 μg/ml
关键词：Helicobacter pylori;Angelica gigas;Coptis japonica;berberine;magnolol;decurcin