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标题：NEUROLOGICAL SYMPTOMS AND MERCURY CONCENTRATION IN THE BRAIN OF MICE FED WITH METHYLMERCURY SALT
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作者：Tsuguyoshi SUZUKI ; Tomoyo MIYAMA
期刊名称：Industrial Health
印刷版ISSN：0019-8366
电子版ISSN：1880-8026
出版年度：1971
卷号：9
期号：1-2
页码：51-58
DOI：10.2486/indhealth.9.51
出版社：National Institute of Occupational Safety and Health
摘要：A hypothesis on the critical concentration of mercury in the brain, which is neces-sary to induce neurological symptoms, was tested again by feeding of methylmercury chloride to mice. As well as in the previous experiment; single or repeated peroral administration of methylmercury chloride to mice, death followed the occurrence of neurological symptoms, when the accumulated amount of mercury was more than 30 μg Hg/g. The most sensitive, namely earliest, symptom; the lessening of the head mainte-nance on horizontal position on being hung with the tail was noticed at a brain con-centration of 10 μg Hg/g. The lowest daily dose group of 10 μg Hg/g of diet did not show the loss of body weight and neurological symptoms during the observation period up to the 41st day of mercury feeding.