文章基本信息

标题：INCREASE IN THE URINARY β2-MICROGLOBULIN AFTER HARD LOADING
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作者：Masana OGATA ; Eiji YUNOKI ; Junko MIZUGAKI 等
期刊名称：Industrial Health
印刷版ISSN：0019-8366
电子版ISSN：1880-8026
出版年度：1978
卷号：16
期号：3-4
页码：103-109
DOI：10.2486/indhealth.16.103
出版社：National Institute of Occupational Safety and Health
摘要：In order to study the factors which have influenced to β₂-microglobulin levels in urine, the effect of hard loading on the concentration of urinary β₂-microglobulin was studied. Increase in both actual and corrected β₂-microglobulin concentration and slight increase in albumin was observed with volunteers in the urine after marathon running. Maximum excretion of urinary β₂-microglobulin was observed 30min after cession of exercise. And increase in actual and corrected β₂-microglobulin concentration, and the ratio of β₂-microglobulin to creatinine in urine of volunteers loaded 210 steps/min for 1 hour were recognized 30 min after cession of exercise by training machine. Similar result of urinary excretion to β₂-microglobulin was obtained with those of creatinine. Concentration of β₂-microglobulin in serum had a tendency to increase, but concentration of creatinine in serum was not increased. Results of Sephadex G-100 gel filtrations indicated that urinary β₂-microglobulin after exercise, which measured by radioimmunoassay, was contained in the filtrated fraction having molecular weight of approximately 11, 800, suggesting that similar substance to HL-A did not excreted in urine after hard loading.