文章基本信息

标题：Associations between White Blood Cell Count and Features of the Metabolic Syndrome in Japanese Male Office Workers
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作者：Noriyuki NAKANISHI ; Mitsuru SATO ; Kokoro SHIRAI 等
期刊名称：Industrial Health
印刷版ISSN：0019-8366
电子版ISSN：1880-8026
出版年度：2002
卷号：40
期号：3
页码：273-277
DOI：10.2486/indhealth.40.273
出版社：National Institute of Occupational Safety and Health
摘要：We assessed the association of white blood cell (WBC) count with different components of the metabolic syndrome (MS) in 5275 Japanese male office workers aged 23-59 years. There was a significantly crude correlation between WBC count and body mass index, systolic and diastolic blood pressures, total cholesterol, high-density lipoprotein cholesterol (negative), triglycerides, fasting plasma glucose, and uric acid (all P<0.001). After controlling for potential confounding factors, the adjusted means of WBC count were significantly higher in subjects with each feature of the MS (obesity, hypertension, hypercholesterolemia, low high-density lipoprotein cholesterol levels, hypertriglyceridemia, high fasting plasma glucose levels, and hyperuricemia) (all P<0.005). The adjusted WBC count increments in subjects with 1, 2, 3, 4, and ≥ 5 features of the MS were 0.28, 0.45, 0.68, 0.76, and 1.40 × 10⁹ cells/l, respectively, compared with the subjects without features of the MS (P for trend<0.001). The adjusted means of WBC count increased significantly with the increasing number of features of the MS in both non-smokers and smokers (both P<0.001). These data indicate a strong association between WBC count and a number of disorders characterizing the MS independent of cigarette smoking among Japanese men.
关键词：White blood cell count;Metabolic syndrome;Cross-sectional study;Japanese men