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  • 标题:Selective Uptake of Dietary Tocotrienols into Rat Skin
  • 本地全文:下载
  • 作者:Saiko IKEDA ; Takako NIWA ; Kanae YAMASHITA
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:2000
  • 卷号:46
  • 期号:3
  • 页码:141-143
  • DOI:10.3177/jnsv.46.141
  • 出版社:Center for Academic Publications Japan
  • 摘要:Using a vitamin E mixture extracted from palm oil, the tissue distribution of dietary tocotrienols and tocopherols was examined in rats and mice. Wistar rats (4-wk-old) were fed a diet containing 48.8mg/kg a-tocopherol, 45.8mg/kg a-tocotrienol and 71.4mg/kg γ-tocotrienol for 8 wk. Nude mice (BALB/c Sic-nu, 8-wk-old) and hairless mice (SKH1, 8-wk-old) were fed the same diet for 4 wk. α-Tocopherol was abundantly retained in the skin, liver, kidney and plasma of rats and mice. α-Tocotrienol and γ-tocotrienol were de-tected slightly in the liver, kidney and plasma, while substantial amounts of these to-cotrienols were detected in the skin of both rats and mice. The present study suggests that the skin is a unique tissue in respect to its ability to discriminate between various vitamin E analogs.
  • 关键词:tocotrienol;vitamin E;rat skin;mouse skin
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