文章基本信息

标题：COLUMBIN ISOLATED FROM CALUMBAE RADIX AFFECTS THE SLEEPING TIME OF ANESTHETIZED MICE
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作者：Keiji WADA ; Toshiyuki KURIHARA ; Masaaki YAGI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1995
卷号：18
期号：4
页码：634-636
DOI：10.1248/bpb.18.634
出版社：The Pharmaceutical Society of Japan
摘要：In a screening series of bioactive components in edible and medicinal plants, we found that Calumbae Radix (Colombo root, 1% powdered feed, for 5 d) and its component, columbin (20-40 mg/kg/d, for 5 d, orally), shortened the sleeping time induced by a urethane and α-chloralose mixture and prolonged the sleeping time induced by hexobarbital in mice.
关键词：columbin;anesthetic;sleeping time;urethane;hexobarbital