文章基本信息

标题：Inhibition of Purified Human Sucrase and Isomaltase by Ethanolamine Derivatives
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作者：Toshiko KANO ; Yoshiko USAMI ; Tetsuo ADACHI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1996
卷号：19
期号：3
页码：341-344
DOI：10.1248/bpb.19.341
出版社：The Pharmaceutical Society of Japan
摘要：Sucrase-isomaltase complex was purified from human intestinal mucosa. Immunostaining shows that sucrase-isomaltase is confined to the area of the striated cell borders of human small intestinal absorptive cells of the villus. Inhibition of sucrase and isomaltase activity by ethanolamine derivatives was investigated. Tris inhibits both types of enzyme activity and is the strongest inhibitor of the ethanolamine derivatives investigated. Bis-Tris inhibited sucrase more than isomaltase. On the other hand, mono-, di- and tri-ethanolamine were weak inhibitors of sucrase but not isomaltase.
关键词：sucrase-isomaltase;human intestine;inhibitor