文章基本信息

标题：Hepatitis B Virus, Hepatitis C Virus and Human T Lymphotropic Type I Among Institutionalized Mentally Retarded Patients in Okinawa, Japan
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作者：Jun Hayashi ; Koya Nakashima ; Miki Hirata 等
期刊名称：Journal of Epidemiology
印刷版ISSN：0917-5040
电子版ISSN：1349-9092
出版年度：1992
卷号：2
期号：1
页码：1-5
DOI：10.2188/jea.2.1
出版社：Japan Epidemiological Association
摘要：During the period 1986-1991 in Okinawa, Japan, serologic markers of hepatitis B virus infection (hepatitis B surface antigen : HBsAg, antibody to hepatitis B core antigen : anti-HBc), hepatitis C virus infection (antibody to HCV : anti-HCV) and human T lymphotropic virus type (antibody to HTLV-I: anti-HTLV-I) were investigated in institutionalized mentally retarded patients. In 1986, HBsAg was detected in 34(9.1%), anti-HBc in 179(48.0%), anti-HCV in 5(1.3%)and anti-HTLV-I in 34(9.1%) of 373 patients. HBsAg and anti-HBc were more prevalent in patients than in the 400 controls (3.8%, p<0.05, 25.5%, p<0.001, respectively). However, there was no significant difference in the prevalence of either anti-HCV or anti-HTLV-I between patients and controls (1.0%, 9.0%, respectively). Eight (12.5%) of 64 seronegative patients not given hepatitis B vaccine were infected with hepatitis B virus (one became an HBsAg carrier)over five years of observation, whereas none were infected with hepatitis C virus or HTLV-I.Hepatitis B virus was the most transmissible of the three viruses among the mentally retarded patients in these institutions.
关键词：hepatitis B virus;hepatitis C virus;human T lymphotropic virus type I;institution;mentallyretarded patients