文章基本信息

标题：Induction of Cytokines by a Phenylpropanoid Glycoside Acteoside
本地全文：下载
作者：Makoto INOUE ; Mari UEDA ; Yukio OGIHARA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1998
卷号：21
期号：12
页码：1394-1395
DOI：10.1248/bpb.21.1394
出版社：The Pharmaceutical Society of Japan
摘要：A phenylpropanoid glycoside acteoside was found to induce interleukin (IL)-1, IL-6, and tumor necrosis factor-α(TNF-α) in macrophage-like cell line J774.A1 at 1-100 ng/ml. In a addition, when the stimulatory action of acteoside was studied using the bovine glomerular endothelial cell line GEN-T, it stimualted IL-6 production. These stimulatory activities were not abolished by treatment with polymixin B, which inactivates lipopolysaccharide (LPS), indicating that the action was not a contamination of LPS.
关键词：acteoside;phenylpropanoid;interleukin-1;interleukin-6;tumor necrosis factor-α