文章基本信息

标题：Sulfation of Parabens and Tyrosylpeptides by Bacterial Arylsulfate Sulfotransferases
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作者：DongHyun KIM ; Byungtaek KIM ; HyungSoo KIM 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1994
卷号：17
期号：10
页码：1326-1328
DOI：10.1248/bpb.17.1326
出版社：The Pharmaceutical Society of Japan
摘要：Arylsulfate sulfotransferase purified from Eubacterium A-44 has higher specific activity than the enzymes from Klebsiella K-36 and Haemophilus K-12. Propylparaben and butylparaben were good substrates among several parabens. The antibacterial activity of parabens was reduced by the sulfation of the phenolic hydroxy group. Tyrosine-containing peptides, kyotorphin, enkephalin and cholecystokinin non-sulfate, were effective as acceptor substrates by A-44, K-36 and K-12 sulfotransferases.
关键词：arylsulfate sulfotransferase;paraben;tyrosylpeptide;intestinal bacteria