文章基本信息

标题：Studies of Cuticle Drugs from Natural Sources. IV. Inhibitory Effects of Some Arctostaphylos Plants on Melanin Biosynthesis
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作者：Hideaki MATSUDA ; Masayuki HIGASHINO ; Yoshiaki NAKAI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1996
卷号：19
期号：1
页码：153-156
DOI：10.1248/bpb.19.153
出版社：The Pharmaceutical Society of Japan
摘要：The inhibitory effect of 50% ethanol extracts obtained from the leaves of six Arctostaphylos plants (A. patula, A. viscida, A. canescens, A. columbiana, A. nevadensis and A. uva-ursi) (Ericaceae) was tested on melanin biosynthesis. Among them, the extracts of A. patula and A. viscida showed potent inhibition against tyrosinase. The two extracts not only inhibited the production of melanin from dopachrome by autoxidation, but exhibited SOD (superoxide dismutase)-like activity and had a moderate absorbance in the UV-B area. These results suggest that the leaves of Arctostaphylos plants, especially A. patula and A. viscida can be applied to a whitening agent for the skin.
关键词：Arctostaphylos patula;Arctostaphylos viscida;melanin;tyrosinase inhibition;hyperpigmentation;whitening agent