文章基本信息

标题：Antiangiogenic Activity of Tumor Necrosis Factor-α Production Regulators Derived from Thalidomide
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作者：Rumiko SHIMAZAWA ; Hiroyuki MIYACHI ; Hisae TAKAYAMA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1999
卷号：22
期号：2
页码：224-226
DOI：10.1248/bpb.22.224
出版社：The Pharmaceutical Society of Japan
摘要：Recently, we developed novel tumor necrosis factor (TNF)-α production regulators with a phthalimide skeleton derived fromthalidomide. We show here that some of these compounds are more potent inhibitors than thalidomide of angiogenesis induced by basic fibroblast growth factor in a murine angiogenesis assay.
关键词：thalidomide;antiangiogenesis;phthalimide;tumor necrosis factor-α