文章基本信息

标题：IN VITRO CONVERSION OF 2, 3-OXIDOSQUALENE INTO DAMMARENEDIOL BY PANAX GINSENG MICROSOMES
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作者：Tetsuo KUSHIRO ; Yoshimi OHNO ; Masaaki SHIBUYA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1997
卷号：20
期号：3
页码：292-294
DOI：10.1248/bpb.20.292
出版社：The Pharmaceutical Society of Japan
摘要：(RS)-[3-³H]-2, 3-Oxidosqualene (1) was converted into (20S)-dammarenediol (2) and not to (20R)-dammarenediol by a microsomal fraction preparaed from the hairy root of Panax ginseng. The enzyme activity was highest at pH 6.0 and was not increased by the addition of any detergents. These properties differed significantly from those of other 2, 3-oxidosqualene cyclases reported from higher plants and animals.
关键词：2, 3-oxidosqualene;dammarenediol;Panax ginseng