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标题：Studies of the Active Substances in Herbs Used for Hair Treatment. II.Isolation of Hair Regrowth Substances, Acetosyringone and Polyporusterone A and B, from Polyporus umbellatus Fries
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作者：Hitoshi ISHIDA ; Yasunori INAOKA ; Jun-ichi SHIBATANI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1999
卷号：22
期号：11
页码：1189-1192
DOI：10.1248/bpb.22.1189
出版社：The Pharmaceutical Society of Japan
摘要：Fractionation of the 50% ethanol extract of Polyporus umbellatus Fries by column chromatography on Amberlite XAD-2, silica gel, Sephadex LH-20 and octadecyl silica gel (ODS) (C18) monitored by a hair-regrowth activity assay, afforded three active principles, 1, 2 and 3. The structures of 1, 2 and 3 were determined as acetosyringone, polyporusterone A, and polyporusterone B by comparison of their spectral data with that of authentic samples, respectively. The effects of several compounds related to acetosyringone, 3, 4-dihydroxybenzaldehyde or polyporusterone A on hair regrowth were also investigated.
关键词：Polyporus umbellatus Fries;acetosyringone;24S-polyporusterone A;polyporusterone B;C3H/He mouse;hair regrowth