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标题：Effect of Epinephrine of GLUT2 Protein Content in Mouse Liver
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作者：Toshihiro MIURA ; Motoshi KATO ; Naoki IWAMOTO 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2000
卷号：23
期号：11
页码：1374-1376
DOI：10.1248/bpb.23.1374
出版社：The Pharmaceutical Society of Japan
摘要：The intraperitoneal administration of epinephrine (EP) to mice caused a significant increase in the blood glucose level and a significant decrease in the liver glycogen content 1 h after its administration at 0.6 mg/kg (blood glucose; p<0.01, liver glycogen; p<0.01). The liver type glucose transporter (GLUT2) mRNA expression and protein content from mouse liver significantly increased in the intraperitoneally EP-treated mice when compared to that in normal mice (mRNA; p<0.01, protein; p<0.01). These results suggest that the hyperglycemic effect of EP is due, at least in part, to the increase of GLUT2 protein synthesis.
关键词：epinephrine;GLUT2;blood glucose;glycogen