文章基本信息

标题：DOES BACITRACIN HAVE AN ABSORPTION-ENHANCING EFFECT IN THE INTESTINE?
本地全文：下载
作者：Shinji GOTOH ; Reiko NAKAMURA ; Mizue NISHIYAMA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1995
卷号：18
期号：5
页码：794-796
DOI：10.1248/bpb.18.794
出版社：The Pharmaceutical Society of Japan
摘要：We studied the absorption enhancement effects of three types of protease inhibitors, aprotinin, bacitracin and soybean trypsin inhibitor, in the rat intestine. Of these protease inhibitors, bacitracin enhanced the absorption of FD-4 and phenol red from the rat small and large intestine without mucosal toxicity. Thus, it was suggested that bacitracin has not only a protease-inhibitory but also an absorption-enhancing capability.
关键词：protease inhibitor;bacitracin;fluorescein isothiocyanate dextran;phenol red;intestinal absorption;absorption enhancement