文章基本信息

标题：Cytotoxic Activities of Solanum Steroidal Glycosides
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作者：Takanori NAKAMURA ; Chieko KOMORI ; Yun-yun LEE 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1996
卷号：19
期号：4
页码：564-566
DOI：10.1248/bpb.19.564
出版社：The Pharmaceutical Society of Japan
摘要：Cytotoxic activities of 20 steroidal glucosides obtained from Solanum genera plants were examined against various cell lines to provide new evidence as follows : 1) As regarding the sugar linkage, the glucosides possessing a β-chacotriosyl moiety were the most effective and the presence of the terminal rhamnosyl residue was required for exhibiting strong activity. 2) As for the aglycone, the glycosides carrying a spirostanol aglycone showed the strongest activity and even an aglycone without a sugar linkage presented considerably strong activity.
关键词：cytotoxic activity;Solanum alkaloid;steroidal glycoside;β-chacotriosyl moiety