文章基本信息

标题：NORRETICULINE AND RETICULINE AS POSSIBLE NEW AGENTS FOR HAIR GROWTH ACCELERATION
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作者：Koichi NAKAOJI ; Hidekazu NAYESHIRO ; Takao TAKAHASHI 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1997
卷号：20
期号：5
页码：586-588
DOI：10.1248/bpb.20.586
出版社：The Pharmaceutical Society of Japan
摘要：(S)-Norreticuline and (S)-reticuline have been shown to stimulate the proliferation of cultured cells from the murine hair apparatus significantly. Furthermore, these activities were found on cultured hair cells, but not on cultured keratinocytes or fibroblasts from murine skin. In addition, (S)-norreticuline significantly stimulated mouse hair regrowth. These results suggest that (S)-norreticuline and (S)-reticuline could have specific activities on hair apparatus cells and might be useful as active compounds for accelerating hair growth.
关键词：hair cell;proliferation;benzylisoquinoline;alkaloid;norreticuline;reticuline