文章基本信息

标题：Continuous Microinstillation of Phenol Red on Liver Surface for Liver Site-Selective Delivery
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作者：Junzo NAKAMURA ; Yayoi YOSHIDA ; Kunihiro MERA 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：1999
卷号：22
期号：7
页码：713-715
DOI：10.1248/bpb.22.713
出版社：The Pharmaceutical Society of Japan
摘要：We report a very promising approach for liver site-selective drug delivery through drug instillation on liver surface. Phenol red, which was selected as a model drug, was accumulated in the instillation site after instillation on the rat liver surface. The site-selective localization was enhanced by gradually and continuously instilling a small amount of drug solution on the liver surface.
关键词：drug delivery system;liver;continuous microinstillation;liver surface;phenol red