This paper aims at exploring the role of the university managerial systems and policies in the process of implementing the concept of entrepreneurship and innovation by Jordanian universities. A questionnaire was used as a means of data collection. Seven Jordanian universities were chosen from both governmental and private sectors and 320 questionnaires were distributed to a random sample of managerial staff of these seven universities. The resulting data was carefully viewed, audited and statistically analyzed using the most appropriate statistical tests. The outcomes and results of the statistical analysis clearly indicated that the three independent variables (i.e. The university managerial process related to conducting the entrepreneurial concept implementation problems and obstacles, the university general managerial and financial policies and managerial staff awareness of entrepreneurial aspects) had a positive impact on both dependent variables individually and collectively (i.e. university expansion and the consolidation of university competitive advantage).