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标题：Absorption of phytol from dietary chlorophyll in the rat
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作者：James H. Baxter ; Daniel Steinberg
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1967
卷号：8
期号：6
页码：615-620
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：The fate of ingested chlorophyll—particularly of the phytol portion of the molecule—was studied. Uniformly ¹⁴C-labeled pheophytin a (the Mg-free derivative of chlorophyll a ) was prepared from an extract of tobacco leaves grown in ¹⁴CO₂, and was administered by stomach tube to rats in which the thoracic duct had been cannulated. Only about 2% of the administered radioactivity was absorbed in 24 hr, largely into the thoracic duct lymph. Moreover, only a fraction of this lymph radioactivity was derived from phytol (i.e., was found in phytol, phytenic acid, or phytanic acid). The results indicated that not more than 1-2% of chlorophyll phytol is available for absorption by the rat. Similarly, after the administration of whole spinach or spinach extract (not labeled) to rats, only about 1% of the total phytol content was absorbed into the intestinal lymph. Nearly all of the administered phytol was found in the feces and the contents of the colon, and was still largely in the form of pheophytin. The study also indicated that little of the nonphytol portion of the chlorophyll molecule is absorbed.
关键词：chlorophyll ; U-¹⁴C-pheophytin a ; spinach ; availability of phytol ; intestinal absorption ; thoracic duct lymph ; phytanic acid ; rat