文章基本信息

标题：Conversion of cholesterol injected into man to cholestanol via a 3-ketonic intermediate
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作者：R. S. Rosenfeld ; Barnett Zumoff ; Leon Hellman 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1967
卷号：8
期号：1
页码：16-23
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：Cholesterol-3-³H,4-¹⁴C was injected intravenously in man and its transformation to cholestanol was studied. From the ³H:¹⁴C ratios in cholestanol isolated from blood, evidence for the participation of a ketonic intermediate in the conversion was obtained. In a second subject given cholestanol-3-³H,4-¹⁴C the ³H:¹⁴C ratios in blood sterols remained unchanged for as long as 1 wk after the injection, which showed that cholestanol did not lose tritium by interconversion with cholestanone.
关键词：cholesterol-cholestanol conversion ; ketonic intermediate ; man ; cholesterol-3-³H,4-¹⁴C metabolism