文章基本信息

标题：Enzymatic synthesis of cytidine diphosphate diglyceride
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作者：James R. Carter ; Eugene P. Kennedy
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1966
卷号：7
期号：5
页码：678-683
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：Evidence is presented for the enzymatic formation of cytidine diphosphate diglyceride in microsomal preparations from guinea pig liver according to the reaction: CTP + phosphatidic acid ⇌ CDP-diglyceride + P—O—P. Conditions have been found in which the incorporation of labeled CTP into CDP-diglyceride is almost entirely dependent upon added phosphatidic acid. The incorporation of CMP into lipid is very slight. A substantial net synthesis of CDP-diglyceride takes place under these conditions. Some properties of the enzyme system are described.
关键词：cytidine nucleotide ; CDP-diglyceride ; enzymatic ; biosynthesis ; phosphatidic acid ; microsomes ; guinea pig ; liver ; dependence ; physicochemical dispersion state