文章基本信息

标题：Decarboxylation of 2-keto fatty acids by brain
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作者：W. Ewart Davies ; Amiya K. Hajra ; Surendra S. Parmar 等
期刊名称：JLR Papers In Press
印刷版ISSN：0022-2275
电子版ISSN：1539-7262
出版年度：1966
卷号：7
期号：2
页码：270-276
语种：English
出版社：American Society for Biochemistry and Molecular Biology
摘要：An enzyme system consisting of washed acetone powder of pig brain, adenosine triphosphate, nicotinamide adenine dinucleotide, magnesium, fumaric acid, and ascorbic acid was found to catalyze the oxidative decarboxylation of 2-ketostearic acid. The products were carbon dioxide and heptadecanoic acid. Washing the enzyme powder with ethylenediaminetetraacetate and other chelating agents destroyed the activity. Further properties of the enzyme system are described. It is believed that this enzyme system accounts in part for the 1-carbon degradation route for brain fatty acids.
关键词：2-ketostearic acid ; decarboxylation ; brain ; pig ; ascorbic acid ; fumaric acid ; iron ; fatty acid catabolism